The “Hot Cross Bun” Sign in Leptomeningeal Carcinomatosis

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The hot cross bun sign.

Hot cross bun sign refers to the cruciform-shaped hyperintensity on T2W axial magnetic resonance images (MRI) in multisystem atrophy due to the selective loss of myelinated transverse pontocerebellar fibers and neurons in the pontine raphe and sparing of the pontine tegmentum and corticospinal tracts [Figure 1, Figure 2].[1] The name derives from a sweet spiced bun baked by the Christian church...

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Hot cross bun sign in a case with multisystem atrophy

A 65-year-old man came to our clinic with progressive disequilibrium and gait problem since 6 years. During this period, he had also urinary incontinency. On neurologic examination, he had scanning speech and bidirectional nystagmus. There was hypokinesia in upper and lower limbs and on cerebellar tests finger to nose and heel to shin were impaired (severe dysmetria); he was unable to walk with...

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"Hot cross bun" sign in variant Creutzfeldt-Jakob disease.

Disease The “hot cross bun” sign refers to pontine cruciform hyperintensity on long TR sequences, which can be observed in multiple-system atrophy, spinocerebellar atrophy types 2 and 3, and in parkinsonism secondary to vasculitis. It has not been previously demonstrated in variant Creutzfeldt-Jakob disease (vCJD), to our knowledge. A 16-year-old girl, diagnosed with vCJD at age 14 years and de...

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'Hot-cross bun sign' of multiple system atrophy.

OBJECTIVE To investigate whether proton density-weighted imaging can detect the "hot cross bun" sign in the pons in multiple system atrophy with predominant cerebellar ataxia significantly better than T2-weighted imaging at 3T. METHODS Sixteen consecutive patients with multiple system atrophy with predominant cerebellar ataxia according to the Consensus Criteria were reviewed. Axial unenhance...

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‘Hot cross bun’ sign with leptomeningeal metastases of breast cancer: a case report and review of the literature

BACKGROUND The 'hot cross bun' (HCB) sign refers to a cruciform-shaped hyperintensity within the pons found on T2-weighted magnetic resonance imaging (MRI). It is commonly associated with atrophy of the pons, cerebellum, and putamen in multiple system atrophy (MSA). In this report, we describe a rare case of the HCB sign in an adult female patient with leptomeningeal metastases of breast cancer...

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ژورنال

عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques

سال: 2013

ISSN: 0317-1671,2057-0155

DOI: 10.1017/s0317167100014736